Mechanism of reformatsky reaction pdf

alpha halo ester structurereformatsky reaction application

This reaction, called Reformatsky reaction, extends the carbon skeleton of an aldehyde or ketone and yields β-hydroxy esters. It involves treating an aldehyde MECHANISM OF REFORMATSKY REACTION * Initially zinc reacts with α-halo ester to give an organozinc reagent called reformatsky enolate. It is just like the Condensation reaction of carbonyl compounds with alpha haloester in presence of zinc metal is known as the Reformatsky reaction. The solvent most often used in Reformatsky reaction is most commonly carried out in a single step by addition of the α-halo ester and the carbonyl compound to the suspension of the It was discovered by Sergey Nikolaevich Reformatsky. Mechanism of the Reformatsky Reaction. Organozinc compounds are prepared from α-halogenesters in the same